Bio-Enhanced® Na-RALA, an 80% active R-lipoic acid powder,
is stable, extremely low (<2.0 %) in insoluble polymer and
offers an innovative solution for capsules, tablets and powdered
drink mixes.
Contains approximately 10% Na and 10% carbonate, bicarbonate and
hydroxide.
Soluble in water: 1 g dissolves in 50 ml water at room
temperature.
Significantly more bio-available than R-lipoic acid (RLA).
- On a weight basis Bio-Enhanced® Na-RALA reaches a Cmax 21 times
higher than RLA.
Melting point at 240° ~ 250° C (with decomposition beginning at
(~210° C).
Free flowing, heat stable up to 85° C and ready for blending with
excipients.
Off-white to yellowish powder, with 80% active R-lipoic acid.
Advantages:
Increased stability: Bio-Enhanced® Na-RALA requires no
refrigeration and has a shelf life of at least 3 years without
polymerization.
Solid R-Lipoic Acid is prone to quickly polymerize upon exposure to
heat, light, and moisture.
Increased Solubility: cleanly soluble in water, whereas RLA is
poorly soluble.
No Solvent Residues: due to the low melting point of the lipoic
acid crystalline structure, there is a tendency for RLA to hold on
to high amounts of cyclohexane, ethyl acetate or toluene.
The additional processing necessary to make Bio-Enhanced® Na-RALA
removes the residual solvents.